Police were called to the accident on Fence Avenue, in which a 64-year-old man from Macclesfield had come off his bike, on Sunday 2nd December at 10.35am.
He was taken to Macclesfield District General Hospital but sadly died a short time later.
No other vehicle was involved in the accident, which happened near the King’s School but on a road that is otherwise largely residential.
Police have appealed for witnesses.
Another motorcyclist was killed following an accident in Macclesfield on October 25.
Terry Neild, 30, died after a collision with a lorry at the busy Flower Pot junction of Congleton Road.
Councillor Janet Jackson, from Macclesfield Town Council and Cheshire East Council, said: “It is a really terrible time. We have had two fatalities close together. This one is on a comparatively quiet road although it can be used as a cut through by people. There is more and more traffic on the roads and Fence Avenue is getting used more. With parked cars and bollards on the road it is a bit of an obstacle course. It is very sad news. More and more people are choosing motorbikes or mopeds as a cheap and convenient form of transport.”
Police are still investigating the Fence Avenue incident and a post mortem is set to take place as they attempt to establish the cause of the accident.
A Cheshire police spokesman said: “Police attended the scene and found that a man had fallen from his motorcycle. The motorcyclist, a 64-year-old local man, was taken to Macclesfield District General Hospital. Sadly, despite the best efforts of the emergency services, he passed away a short time later.”
Anyone with information is asked to contact Cheshire police on 101 quoting incident number 257729.