The incident, which took place on June 8 at the M6 service station, saw the four bikers taken to hospital by both ambulance and air ambulance.
Their injuries were not life threatening, and all have since been discharged from hospital. A closure was put in place on the M6 northbound carriageway following the brutal attack.
The case was then closed with no arrests made – and the attacker or attackers still at large.
At the time of the incident, police say they were called shortly after 2pm following reports of a ‘disturbance’ at the service station.
A statement released by Cheshire Constabulary said: “At 2.02pm on Saturday 8 June police received reports of four men on motorbikes having received stab wounds following a disturbance at Knutsford services on the M6.
“Four men have been taken to hospital by ambulance and air ambulance with injuries not believed to be life threatening. Officers will be patrolling Knutsford services to provide reassurance. A closure was put in place between junction 19 to junction 20 on the M6 northbound but this has now been lifted.”